Competing on the edge.

نویسنده

  • Massimo Scanziani
چکیده

Fast-acting neurotransmitters can exit the synaptic cleft and bind to extrasynaptic receptors. This process is modulated by transmitter uptake mechanisms (transporters). A new study focusing on glutamate-mediated transmission in the cerebellum describes the specific role of neuronal transporters in modulating the access of glutamate to extrasynaptic metabotropic glutamate receptors, and reveals important consequences of extrasynaptic signaling on synaptic plasticity.

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عنوان ژورنال:
  • Trends in neurosciences

دوره 25 6  شماره 

صفحات  -

تاریخ انتشار 2002